EMERGING UNDERSTANDING OF MULTISCALE TUMOR HETEROGENEITY

Emerging understanding of multiscale tumor heterogeneity

Cancer is a multifaceted disease characterized by heterogeneous genetic alterations and cellular metabolism, Course a pied - Femme - Vetements - Singlet at the organ, tissue, and cellular level.Key features of cancer heterogeneity are summarized by ten acquired capabilities, which govern malignant transformation and progression of invasive tumors.T

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Microstructure and mechanical properties of 3D-GH3536/R-GH3128 butt joint welded by fiber laser welding with focus rotation

In this paper, the focus rotation has been adopted in the fiber laser butt welding of 4 mm thick Selective Laser Melting GH3536 and rolled solid solution GH3128.The weld morphology, microstructure, microhardness, joint strength and fracture morphologies were analyzed by using an optical microscope (OM), a scanning electron microscope Reference Mate

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In vivo lineage tracing reveals Axin2-expressing, long-lived cortical thymic epithelial progenitors in the postnatal thymus.

In the thymus, cortical and medullary thymic epithelial cells (TECs) are instrumental for generating a repertoire of functional T cells.Hence, there has been much interest in the ontogeny of TECs.While medullary TEC (mTEC) and bipotent progenitors have been identified, the existence of a cortical TEC (cTEC) progenitor remains ambiguous.In this stud

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Facet Cyst Haematoma in the Lumbar Spine: A Report of Four Cases

We present 4 cases of facet cyst haematoma in the ligamentum flavum of the lumbar spine.All patients AC Adaptor for PT Touch presented with a one-to-3-month history of back pain or numbness in the legs, and sudden neurological deterioration.One also developed cauda equina syndrome and another developed radiculopathy.In all cases, magnetic resonance

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